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With another defensive star out, can the 49ers’ offense rise to the challenge against Rams?

Credit: Getty Images/iStockphoto/DigtialStorm

With another defensive star out, can the 49ers’ offense rise to the challenge against Rams?

McCarthy’s leadership comes with ease for Vikings, who face another back-on-track team in the Ravens

McCarthy’s leadership comes with ease for Vikings, who face another back-on-track team in the Ravens

Revived Ravens make 1st visit to Minnesota with Lamar Jackson in latest test for Vikings defense

Revived Ravens make 1st visit to Minnesota with Lamar Jackson in latest test for Vikings defense

Lions face Jayden Daniels-less Commanders, looking to rebound after loss

Lions face Jayden Daniels-less Commanders, looking to rebound after loss

Panthers’ Rico Dowdle turns attention on ‘2 pumps’ fine into opportunity to raise funds for charity

Panthers’ Rico Dowdle turns attention on ‘2 pumps’ fine into opportunity to raise funds for charity

Surging Seahawks face Jacoby Brissett, Cardinals in NFC West matchup

Surging Seahawks face Jacoby Brissett, Cardinals in NFC West matchup

More NFL News

Sauce Gardner eagerly awaits taking the international stage for his Colts debut against Falcons

Sauce Gardner eagerly awaits taking the international stage for his Colts debut against Falcons

LISTEN: Panthers defensive tackle Derrick Brown says a culture change has led to team’s turnaround

LISTEN: Panthers defensive tackle Derrick Brown says a culture change has led to team’s turnaround

Panthers look to build off momentum from big win over Packers when they host NFC South-rival Saints

Panthers look to build off momentum from big win over Packers when they host NFC South-rival Saints

Playoff-contending Bears look to avoid a letdown against the struggling Giants

Playoff-contending Bears look to avoid a letdown against the struggling Giants

Chiefs look to Reid’s post-bye week success to turn season around

Chiefs look to Reid’s post-bye week success to turn season around

Garrett Wilson hated to see trades, but trusts Jets’ vision and excited to return after knee injury

Garrett Wilson hated to see trades, but trusts Jets’ vision and excited to return after knee injury

New Colts CB Sauce Gardner is happy to be in Indy and set to play against the Falcons

New Colts CB Sauce Gardner is happy to be in Indy and set to play against the Falcons

Bears look to avoid letdown against Giants after pulling out wild win against Bengals

Bears look to avoid letdown against Giants after pulling out wild win against Bengals

Colorado Rockies hiring Paul DePodesta of ‘Moneyball’ fame from NFL’s Cleveland Browns to run MLB team, AP source says

Colorado Rockies hiring Paul DePodesta of ‘Moneyball’ fame from NFL’s Cleveland Browns to run MLB team, AP source says

Panthers expected to lean heavily on RB Rico Dowdle in division matchup vs. Saints

Panthers expected to lean heavily on RB Rico Dowdle in division matchup vs. Saints

Chargers trying to figure out offensive line on the fly ahead of stiff test from Steelers

Chargers trying to figure out offensive line on the fly ahead of stiff test from Steelers

Houston Texans’ sister company purchases women’s volleyball team

Houston Texans’ sister company purchases women’s volleyball team

Bizarrap, Daddy Yankee to headline halftime show at NFL’s first game in Spain

Bizarrap, Daddy Yankee to headline halftime show at NFL’s first game in Spain

Dolphins seek redemption against Bills after costly errors in Week 3 loss

Dolphins seek redemption against Bills after costly errors in Week 3 loss

Drake Maye leads Patriots against Baker Mayfield and the Buccaneers in a matchup of division leaders

Drake Maye leads Patriots against Baker Mayfield and the Buccaneers in a matchup of division leaders

Jaguars look to sweep season series when they visit Texans, who will be without Stroud

Jaguars look to sweep season series when they visit Texans, who will be without Stroud

Jags’ Cam Little sends another jersey to Canton but keep his cleats and the record-setting ball

Jags’ Cam Little sends another jersey to Canton but keep his cleats and the record-setting ball

Robert Kraft and Bud Adams among Pro Football Hall of Fame contributor semifinalists

Robert Kraft and Bud Adams among Pro Football Hall of Fame contributor semifinalists

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