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John E. Sununu enters GOP primary race in New Hampshire for US Senate seat he lost in 2008

Study shows depression on the rise among construction workers

Today in History: October 22, Lance Armstrong stripped of Tour titles

See the world in vertical: Top photos by AP’s photojournalists

Israeli settlers beat Palestinian farmers on video as attacks mount during West Bank olive harvest

Immigration agents shot a suspect after he rammed their vehicle during a LA stop, DHS says

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Winning numbers drawn in Tuesday’s Mega Millions

Youth anger in Ivory Coast as the 83-year-old president seeks a fourth term

Tropical Storm Melissa brings heavy rain and a flood risk to Haiti, Dominican Republic and Jamaica

North Korea test-fires ballistic missiles ahead of Trump’s Asia trip

Immigration agents conducting sweep on NYC’s famed Canal Street confronted by protesters

Florida sets execution date for man who raped and murdered his former manager at a convenience store

Alabama board seeks to ban books that ‘positively’ depict trans themes from library youth sections

New Jersey Republicans ask for federal monitors in critical county ahead of governor’s election

Chess grandmaster Daniel Naroditsky is remembered as a leader in the game’s online surge

An elephant family smashed pumpkins at the Oregon Zoo. But this baby just wanted to play ball

Democrats look to long term as North Carolina GOP redistricting plan seeks another seat for Trump

The top photos of the day by AP’s photojournalists

Suspected explosive device found and brought indoors prompts Wyoming Capitol evacuation

Meta expands teen accounts to Facebook and Messenger, critics say more needs to be done

Maine Democrat Platner, on defense over tattoo, takes page from Trump playbook to keep up Senate bid

New York police seek woman for questioning after baby is abandoned at Penn Station subway stop

Sea cucumbers wash ashore by the thousands in a coastal Oregon town

The Latest: Trump hosts GOP senators at White House as shutdown drags on