SAN FRANCISCO (4-5) at NEW ORLEANS (6-2)
Sunday, 4:25 p.m. ET, Fox
OPENING LINE – Saints by 6 ½
RECORD VS. SPREAD – 49ers 5-4, Saints 3-5
SERIES RECORD – 49ers lead 49-26-2
LAST MEETING – 49ers beat Saints 48-46 on Dec. 8, 2019, in New Orleans
LAST WEEK – 49ers lost to Packers 34-17; Saints won 38-3 at Tampa Bay
AP PRO32 RANKING – 49ers No. 18, Saints No. 3
49ERS OFFENSE – OVERALL (13), RUSH (12), PASS (17)
49ERS DEFENSE – OVERALL (7), RUSH (10), PASS (8)
SAINTS OFFENSE – OVERALL (9), RUSH (11), PASS (9)
SAINTS DEFENSE – OVERALL (3), RUSH (2), PASS (12)
STREAKS, STATS AND NOTES: The 49ers are the 22nd defending conference champion to have a losing record through nine games. Only three of the previous 31 rebounded to make the playoffs (2018 Eagles, 2015 Seahawks, 1995 Chargers). … WR Richie James Jr. had 184 yards receiving and one TD last week. The only other 49ers players to reach those numbers in a game since the merger are Jerry Rice (four times), Terrell Owens, George Kittle, John Taylor and Anquan Boldin. … James had three catches for at least 40 yards in that game, becoming the first player since Tyreek Hill in 2017 to do that in a game and the first 49ers player to do it since Jerry Rice in 1995. … The 49ers have started 46 players this season, the third most for the franchise since the merger to the 47 in 2005 and 69 in 1987 when replacement players played three games. … San Francisco QB Nick Mullens has thrown for at least 250 yards in eight of 11 career starts. … The Niners have generated at least 10 yards on 131 plays from scrimmage, the fifth most in the NFL this season. … San Francisco LB Fred Warner is the only player in the NFL with at least 65 tackles, three passes defensed and two INTs this season. … The Niners have committed at least two turnovers in three straight games for the first time since 2018. … New Orleans has won five straight and leads the NFC South Division, which it has won each of the past three seasons. … QB Drew Brees passed for a season-high four TDs vs. no INTs for a 135.2 rating last week. … Brees has 37 games with four-plus TD passes, the most in NFL history. … Reserve QB and utility player Taysom Hill passed for 48 yards and had 75 scrimmage yards (career-high 54 rushing, 21 receiving) last week. … RB Alvin Kamara had a TD rushing last week, his fifth this season. Kamara leads the NFL with 1,036 scrimmage yards (565 receiving, 471 rushing) and can become the first player with 500-plus yards rushing and receiving in each of his first four seasons in NFL history. … WR Michael Thomas had 11 receptions for 134 yards and a TD in the last meeting. … WR Emmanuel Sanders played for the 49ers in the previous meeting, when he had seven catches for 157 yards and a touchdown and also threw a 35-yard TD pass. … Sanders had his third TD receiving this season last week after missing the Saints’ previous two games on the club’s COVID-19 reserve list. … DE Trey Hendrickson had two sacks last week and has a career-high 7 1/2 sacks this season. … DT David Onyemata had his first-career INT in Week 9 and has three sacks this season. … S Malcolm Jenkins had his first INT of the season in Week 9. … Fantasy tip: Sanders could be in for a big game against his old team if the 49ers’ defense is scheming primarily to stop Kamara and Thomas.
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