UPS AND DOWNS NEW YORK (AP) _ The following list shows the Nasdaq stocks and warrants that have gone up the most and down the most based on percent of change. Only securities with closing prices or previous closing prices of at least $2 and at least 1000 shares traded are included. Net and percentage changes are the difference between last week’s closing price and this week’s closing price. UPS Name LastChgPct.

1MadrigPhr
273.56+209.76 Up328.8
2EdesaBioth 2.11 +1.16 Up121.9
3Expion360n 2.35 +1.26 Up115.6
4VikingThera 8.45 +4.43 Up110.2
5OricPhrma 5.78 +2.66 Up 85.3
6ProQRThera 2.71 +1.15 Up 73.7
7VeronaPhrm 21.89 +8.76 Up 66.7
8YumanityThrs 4.96 +1.74 Up 54.0
9InflaRx 3.25 +1.10 Up 51.2
10SolunaHldgpf 2.39 +.81 Up 51.1
11Neovascrs 15.00 +4.96 Up 49.4
12Perpetua 2.80 +.92 Up 48.9
13EverQuote 15.46 +4.82 Up 45.3
14Wag!Grp 3.12 +.97 Up 45.1
15Rezolute 2.08 +.62 Up 42.5
16Omeros 2.54 +.75 Up 41.9
17MediaBrndpf 9.31 +2.56 Up 37.9
18EvokePharrs 2.62 +.72 Up 37.9
19SophiaGen 2.85 +.74 Up 35.1
20Altimmune 15.33 +3.85 Up 33.5
21OramedPharm 10.95 +2.69 Up 32.6
22Pharvaris 9.91 +2.41 Up 32.1
23ATIFHldgrs 2.27 +.55 Up 32.0
24Alvotechn 10.00 +2.30 Up 29.9
25Celcuity 12.87 +2.86 Up 28.6
DOWNS
Name LastChgPct.
1180LifeMrs 1.24 —3.56 Off 74.2
2HTGMolers 3.10 —3.51 Off 53.1
3MingZhuLg 1.75 —1.77 Off 50.3
4BIMIIntlrs 1.37 .88 Off 39.1
5VeritoneInc 5.03 —2.62 Off 34.2
6Dragonflyn 10.85 —5.46 Off 33.5
7ZyversaTher 2.15 —1.07 Off 33.2
8P3HlthPrtA 2.03 —1.01 Off 33.2
9MicroAlgon 1.45 .67 Off 31.6
10Bionomics 4.71 —2.09 Off 30.7
11ForwdPhr 1.81 .80 Off 30.7
12GossamerB 1.90 .83 Off 30.4
13EntradaThr 14.97 —6.21 Off 29.3
14IClickIntrrs 3.57 —1.44 Off 28.7
15LghtwavLg 4.74 —1.77 Off 27.2
16Meihuan 8.34 —2.96 Off 26.2
17Beyondsprng 1.69 .59 Off 25.9
18CueHealth 2.18 .74 Off 25.3
19CNSPharmrs 2.19 .74 Off 25.3
20ExelaTchpfB 2.34 .78 Off 25.0
21ModularMdn 1.99 .65 Off 24.6
22AutoscpTch 3.80 —1.23 Off 24.5
23FuelCellE 2.67 .84 Off 23.9
24Nuwellirs 7.60 —2.34 Off 23.5
25RedRobin 5.70 —1.72 Off 23.2
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