The Associated Press
The first quarter of the schedule went perfectly for Denver, Seattle, Kansas City and New England.
Peyton Manning threw four more touchdown passes, giving him 16, the most in the first four games of a season. He also passed for 327 yards in a 52-20 rout of Philadelphia. Denver (4-0) has won a team-record 15 straight regular-season games and scored 179 points.
"We were motivated to be on top of our game offensively, to score points, touchdowns, not field goals," Manning said Sunday. "I thought we did that today. We certainly enjoyed that."
Seattle (4-0) rallied from a 17-point hole and won at Houston 23-20 in overtime on Steven Hauschka's 45-yard field goal.
"It was important for our ball club just to win on the road, just to continue our win streak," said cornerback Richard Sherman, whose interception return TD forced overtime. "I think that was important to us, to be that stepping stone, to continue to grow as a team."
Alex Smith threw three touchdown passes, Dexter McCluster returned a punt 89 yards for another score and Kansas City kept the New York Giants winless at 0-4 in a 31-7 rout.
"I know they'll battle," said Chiefs first-year coach Andy Reid, who spent the previous 14 seasons coaching the Eagles. "That's what I know. There are a lot of things I don't know but I do know this: We're a tough bunch."
New England staged a defensive stand after nearly frittering away a late lead and won at Atlanta 30-23.
"We are just griding it out," Tom Brady said. "4-0 is good, we certainly played better, got a lot to learn from."
Two more 3-0 teams, Miami and New Orleans, meet Monday night in the Big Easy.
Chicago fell from the undefeated ranks when it lost 40-32 at Detroit.
Week 4 began when San Francisco (2-2) beat St. Louis (1-3) 35-11 on Thursday night.
Green Bay (1-2) and Carolina (1-2) were off.
BRONCOS 52, EAGLES 20
At Denver, the Broncos set a team record for points -- they have been around 54 years -- with Manning's two TD passes each to Demaryius Thomas and Wes Welker. Manning even sat out the fourth quarter.
Manning also joined Milt Plum in 1960 as the only quarterbacks to throw 16 touchdown passes without an interception.
The Eagles (1-3) have allowed 138 points in four games.
SEAHAWKS 23, TEXANS 20, OT
At Houston, the Seahawks' first 4-0 start in franchise history was aided when Doug Baldwin caught a 7-yard pass and Kareem Jackson was penalized for unnecessary roughness for dumping him into the ground. That got Seattle in field goal range and Hauschka's kick came four plays later.
The Seahawks rallied to tie it at 20-20 on the pick-6 by Sherman in the fourth quarter.
Texans linebacker Brian Cushing sustained a concussion, and Seahawks coach Pete Carroll said defensive end Michael Bennett was OK after being taken off the field on a stretcher after injuring his lower back.
CHIEFS 31, GIANTS 7
Smith had touchdown passes of 4, 2 and 35 yards for the Chiefs, who under Reid have already doubled their victory total of 2012. They are the second team to go from a two-win season to 4-0 the next year, matching the 1980 Lions.
Smith was intercepted twice, the first giveaways by the host Chiefs, who also lost a fumble.
The Giants are 0-4 for the first time since 1987. Eli Manning connected with Victor Cruz on a 69-yard scoring play for New York's only score. The Kansas City defense sacked Manning three times.
PATRIOTS 30, FALCONS 23
At Atlanta, Brady threw for 316 yards and two touchdowns to improve the Patriots to 4-0 for the first time since their perfect regular season of 2007.
Strong defense in the red zone was decisive as Atlanta (1-3) had a chance to tie in the final minute. Matt Ryan's fourth-down pass went off the hands of Roddy White, tightly covered by Aqib Talib, in the end zone with 36 seconds remaining.
Rookie Kenbrell Thompkins finished with six catches for 127 yards, and Julian Edelman chipped in with 118 yards on seven receptions.
LIONS 40, BEARS 32
At Detroit, Reggie Bush's 37-yard touchdown run helped Detroit score 27 points in the second quarter. He accounted for 173 yards of offense as Detroit (3-1) moved into a first-place tie with Chicago (3-1) in the NFC North.
The Lions scored 24 straight points, including three TDs in a span of 3 minutes, 26 seconds, after Matt Forte's 53-yard TD run gave the Bears a 10-6 lead early in the second quarter.